Desmoplastic mesotheliomas are rare forms of the malignant pleural lining. Although only about 5 percent of all mesotheliomas are desmoplastic, the number of cases has steadily increased over time. The tumors in this type of cancer are characterized by dense, paucicellular hyalinized collagen. Typically, these tumors form nodules that resemble benign fibrous tissue. However, imaging scans can be used to identify whether or not a tumor has spread to nearby tissues.
Initially, the disease was diagnosed through an X-ray of the lungs. It looked like tuberculosis, but the X-rays showed something else. A CAT scan was conducted to rule out other causes. A video-assisted thoracoscopic examination revealed inflammatory cells and fibers similar to those of desmoplastic mesothelia.
In a recent study, doctors discovered that the sarcomatoid and biphasic types of mesothelioma have similar survival rates. Patients with desmoplastic malignant mesothelioma have a life expectancy of 3.8 months. The cancer cells in this type form dense, fibrous nodules in the hyalinized connective tissue, making it difficult to diagnose early.
In rare cases, surgeons will operate on the patient’s chest wall. Desmoplastic mesotheliomas rarely respond to surgery. Most patients do not benefit from surgery, although some cases report improved survival after the surgery. Most treatments for desmoplastic mesotheliomes focus on reducing symptoms and prolonging life. Surgical procedures may include pleurodesis, and paracentesis.
Although desmoplastic mesotheliama has a sarcomatoid histology, it is rare in other organs. In addition to pleural lesions, it is also rare to occur in the pericardium, spleen, or pericardium. Most commonly, patients with desmoplastic mesothelithelioma exhibit diffuse opacities, miliary pulmonary nodules, or a localized mass without any pleural lesions.
Surgery is the most common treatment for desmoplastic mesotheli-ma, but is not an effective option for the disease. There are other treatments for desmoplastic mesotiama that target the cancer’s immune system, such as radiotherapy and chemotherapy. The treatments for this rare type of mesothelioma often involve a combination of radiation and chemotherapy.
During a biopsy, the cancer cells form dense, fibrous nodules of hyalinized connective tissue. The cells form nodules that resemble pulmonary fibrosis. In most cases, desmoplastic mesotheli-ma is asymptomatic. Clinical trials are also beneficial for those with desmoplastic mesotheliama because of the fact that they allow doctors to compare the results of the different types of the disease.
Surgical treatment for desmoplastic mesotheli-ma is rare. Surgical treatment for desmoplastic measothelioma has a low success rate due to the high risk of recurrence. In some cases, surgical intervention is the only option. But if the cancer has already spread, it may be too late to offer a cure.
In patients with desmoplastic mesotheli-ma, the disease is very uncommon. Surgical procedures may be necessary. In some cases, desmoplastic mesothelia will respond to certain drugs, but in most cases, the disease will return. In other cases, the patient will experience no treatment. But it is possible to extend the life of the affected individual by undergoing surgery.
Because the desmoplastic subtype of mesothelioma is so rare, it is difficult to accurately diagnose. Even if the patient is diagnosed with the disease, the prognosis is still poor. In rare cases, a treatment can extend the patient’s life. If the patient is already in the advanced stages of the disease, the doctor will try to cure the disease, or at least ease the symptoms.
A 75-year-old male presented with a pleural effusion in his right thoracic cavity. A cytological examination and tumor biopsy did not reveal a specific diagnosis. The tumor was encased in the right lung and invaded the diaphragm. Additionally, it had metastatic lesions in the liver. The tumor was diagnosed as desmoplastic mesotheli-ma.
Unlike sarcomatoid mesothelioma, desmoplastic mesotheli-ma is difficult to diagnose. It is difficult to distinguish it from a sarcomatoid tumor because of its lack of patterns. Usually, the sarcoma tumors are over 50% fibrous, with a bland, patternless pattern.